When Pharmaceutical Industry Start Dealing With Trans- Dermal / Tropical Products, It Is One Of The Most Very Important Part That They Will Have Somany Questions As,how To Start.what Types Of Media Should Be Used.which Membrane Should Be Suitable For Our Us.proper Procedures Of IVRT.before IVPT What Should Be Done.proper Guidelines For Diffusion Process.proper Guidelines For Permiation Process.what Should Berequired As Apparatus For IVRT.what Sample Amount Should Be For IVRT & IVPT.